Dieting is something I talk about every now and then and I’m not an advocate for any specific type of diet. My advice will always be do what works for you because our bodies are all different and what works for one person, may not work for the next person. Our diet choices can also be because of lifestyle. For instance, not everyone has time … Continue reading To diet or not to diet?
I never know how to start a blog post, so let let’s just cut to the chase. Today I’m going to combine two posts because one is fairly small. There is not much news in the world of MC4r, but some results have been published regarding Rhythm Pharmaceuticals Phase 3 Clinical Trial for Bardet-Biedl Syndrome. Overall, patients reported clinically meaningful improvements across multiple health-related quality … Continue reading Genetics or Lifestyle: 60 minute segment sparks debate about the causes of obesity
I think we live in a fantastic age of medicine, and it will only get better with time. I’m so pleased to see the amount of research that is being done into obesity and our genes. It makes me hopeful that one day, when a person says their weight is the cause of a medical condition a person won’t look at them sceptically. To this … Continue reading Study links genetic rearrangement to obesity
I hope all reading this had a very merry Christmas and are looking forward to the new year! I’ve been out of touch lately and I want to post more frequently in the new year. Hopefully with more positive news such as my last post. Hopefully things continue as they have been and 2023 will shape up to be a good year for those of … Continue reading Scientists link second gene to appetite regulation in MC4r gene
Rhythm Pharmaceuticals has announced that IMCIVREE (setmelanotide) has been granted marketing authorisation in Great Britain for treatment of obesity and control of hunger in Bardet-Biedl Syndrome. Firstly this is great news! After the last post I made, I thought it would take months, maybe even years before a drug like this would be given authorisation in the UK, considering how strict someone of their health … Continue reading Christmas has come early for MC4r patients with Bardet-Biedl Syndrome in the UK
In my last post I said something in passing I’d like to talk more about. I’ve had an MC4r deficiency diagnosis for about eight years and in that time I’ve only met one other person who has heard of MC4r. This encounter happened while in the waiting room of a hospital while I was waiting to see my neurologist regarding my migraines. My mum who … Continue reading Why more doctors need to know about MC4r
Last I posted it was with regards to my mental health, while an uphill battle I’m on the mend and seeing better days. I’ve wanted to get back to posting regularly and hope I can put my best foot forward today. I’m going to begin with something that brought a smile to my face when I read it, Rhythm Pharmaceuticals has announced the publication of … Continue reading Rhythm Pharmaceuticals has announced the publication of a children’s book “Gabe’s Story”
The last we heard of Rhythm Pharmaceuticals they were modifying their drug treatment for weight loss following feedback from the FDA. This seemed quite the setback at the time. However, it appears they’ve been successful. Not just once, but twice. Rhythm Pharmaceuticals has announces FDA Approval of IMCIVREE® (setmelanotide) for use in patients with Bardet-Biedl Syndrome. Bardet-Biedl Syndrome is something we’ve touched on very briefly … Continue reading Rhythm Pharmaceuticals launches IMCIVREE for the treatment of obesity
First I’ll start with an apology for being MIA; I’ve had the worst spell of migraine attacks. Unfortunately when I have an attack they can last anywhere between a few days to two weeks and I’ve been down for about two weeks. Still not 100% but on the mend. I’ve had a few things I’ve wanted to talk about, but my brain feels like mush … Continue reading Rhythm Pharmaceuticals modify design of ongoing MC4r treatment following FDA feedback
Before I write most blog posts, I research like a crazy person. My blog is all about MC4r and sometimes other weight-related genetic disorders. It’s about awareness, it’s about breaking down the stigma around obesity, and essentially you can’t judge a book by its cover, and that a persons lifestyle doesn’t always reflect their body type. What I have found recently is that many newspapers … Continue reading GNAS mutations can cause obesity in children due to their affect on MC4r
Recent life news, I’ve changed doctors practices and if you’re familiar with the process then you know you have a review with your new doctor. In preparation I’ve been looking more into MC4r deficiency so I can articulate myself well since most doctors don’t know what is. My hope is that a fresh start with my new doctor will help my mental state better although … Continue reading How oestrogen could impact the MC4r gene in women and possible weight loss treatments
I’ve been a busy little bee, but have come across something fairly interesting. I bring up my childhood frequently — usually in the form of stories and memories that hold significant value to me and my MC4r journey. I bring these up because I think it’s important to understand that a person has demons in their past. Regardless of how small or big they may … Continue reading Why finding out if you have a genetic mutation linked to obesity is important
MC4r and ME 