I think we live in a fantastic age of medicine, and it will only get better with time. I’m so pleased to see the amount of research that is being done into obesity and our genes. It makes me hopeful … Continue reading Study links genetic rearrangement to obesity
I hope all reading this had a very merry Christmas and are looking forward to the new year! I’ve been out of touch lately and I want to post more frequently in the new year. Hopefully with more positive news … Continue reading Scientists link second gene to appetite regulation in MC4r gene
Rhythm Pharmaceuticals has announced that IMCIVREE (setmelanotide) has been granted marketing authorisation in Great Britain for treatment of obesity and control of hunger in Bardet-Biedl Syndrome. Firstly this is great news! After the last post I made, I thought it … Continue reading Christmas has come early for MC4r patients with Bardet-Biedl Syndrome in the UK
In my last post I said something in passing I’d like to talk more about. I’ve had an MC4r deficiency diagnosis for about eight years and in that time I’ve only met one other person who has heard of MC4r. … Continue reading Why more doctors need to know about MC4r
Last I posted it was with regards to my mental health, while an uphill battle I’m on the mend and seeing better days. I’ve wanted to get back to posting regularly and hope I can put my best foot forward … Continue reading Rhythm Pharmaceuticals has announced the publication of a children’s book “Gabe’s Story”
The last we heard of Rhythm Pharmaceuticals they were modifying their drug treatment for weight loss following feedback from the FDA. This seemed quite the setback at the time. However, it appears they’ve been successful. Not just once, but twice. … Continue reading Rhythm Pharmaceuticals launches IMCIVREE for the treatment of obesity
First I’ll start with an apology for being MIA; I’ve had the worst spell of migraine attacks. Unfortunately when I have an attack they can last anywhere between a few days to two weeks and I’ve been down for about … Continue reading Rhythm Pharmaceuticals modify design of ongoing MC4r treatment following FDA feedback
Before I write most blog posts, I research like a crazy person. My blog is all about MC4r and sometimes other weight-related genetic disorders. It’s about awareness, it’s about breaking down the stigma around obesity, and essentially you can’t judge … Continue reading GNAS mutations can cause obesity in children due to their affect on MC4r
Recent life news, I’ve changed doctors practices and if you’re familiar with the process then you know you have a review with your new doctor. In preparation I’ve been looking more into MC4r deficiency so I can articulate myself well … Continue reading How oestrogen could impact the MC4r gene in women and possible weight loss treatments
I’ve been a busy little bee, but have come across something fairly interesting. I bring up my childhood frequently — usually in the form of stories and memories that hold significant value to me and my MC4r journey. I bring … Continue reading Why finding out if you have a genetic mutation linked to obesity is important
It’s time for some good news my friends, Rhythm Pharmaceuticals, Inc. who we’ve spoken about a few times have announced that the European Commission has granted marketing authorization to IMCIVREE in the European Union for the treatment of obesity and … Continue reading Rhythm Pharmaceuticals announces authorization of IMCIVREE for treatment of obesity in the EU
Today we’re going back to basics and talking about the gene that inspired this blog — MC4r. Im always sceptical when I read a headline that says “new research has found…” mostly because in my experience their conclusions are not … Continue reading New research suggest many of us could be carrying 17kg of fat due to a disruptive mutation in the MC4r gene
MC4r and ME 