First I’ll start with an apology for being MIA; I’ve had the worst spell of migraine attacks. Unfortunately when I have an attack they can last anywhere between a few days to two weeks and I’ve been down for about … Continue reading Rhythm Pharmaceuticals modify design of ongoing MC4r treatment following FDA feedback
Before I write most blog posts, I research like a crazy person. My blog is all about MC4r and sometimes other weight-related genetic disorders. It’s about awareness, it’s about breaking down the stigma around obesity, and essentially you can’t judge … Continue reading GNAS mutations can cause obesity in children due to their affect on MC4r
Recent life news, I’ve changed doctors practices and if you’re familiar with the process then you know you have a review with your new doctor. In preparation I’ve been looking more into MC4r deficiency so I can articulate myself well … Continue reading How oestrogen could impact the MC4r gene in women and possible weight loss treatments
I’ve been a busy little bee, but have come across something fairly interesting. I bring up my childhood frequently — usually in the form of stories and memories that hold significant value to me and my MC4r journey. I bring … Continue reading Why finding out if you have a genetic mutation linked to obesity is important
It’s time for some good news my friends, Rhythm Pharmaceuticals, Inc. who we’ve spoken about a few times have announced that the European Commission has granted marketing authorization to IMCIVREE in the European Union for the treatment of obesity and … Continue reading Rhythm Pharmaceuticals announces authorization of IMCIVREE for treatment of obesity in the EU
Today we’re going back to basics and talking about the gene that inspired this blog — MC4r. Im always sceptical when I read a headline that says “new research has found…” mostly because in my experience their conclusions are not … Continue reading New research suggest many of us could be carrying 17kg of fat due to a disruptive mutation in the MC4r gene
This week I set myself a new challenge, and it’s a challenge because it’s something I’ve never done before and something I find quite terrifying. After years of dieting, and monitoring everything I eat… I’ve decided to stop. To an … Continue reading Why dieting with MC4r sucks
Over the last couple of weeks I’ve shared some opinions. You may have agreed with me, you may not but at the end of the day an opinion is just that. An opinion. I don’t pretend to be all knowing. … Continue reading Rhythm Pharmaceuticals’ MC4r agonist drug could be marketed by the end of 2021
I want to talk about something I saw on the news this morning. One thing I hate about news bulletins is how vague they are, this particular one had to do with obesity overtaking smoking in regards to mortality rates, … Continue reading Lets talk about the news and the so called weight loss “wonder drug”
After writing last weeks post I asked myself a question, and weirdly it’s a question I’ve never asked myself before. Do we all have a genetic component when it comes to our weight, or just some of us? Well, I … Continue reading Researchers have linked 300 mutations to the MC4r gene
As stated in an earlier post, I want to talk more about other genetic disorders that are not my own – MC4r deficiency is something I try to educate myself with everyday. A part of me feels like if I … Continue reading Scientists are aware of around 80 different genetic conditions that cause obesity
While I myself have been diagnosed with “MC4r deficiency” and it’s something I try to understand more everyday. There are a number of genetic causes of obesity, that usually link to MC4r that I feel I should talk about as … Continue reading Rhythm Pharmaceuticals’ MC4r agonist drug shows promising results in Phase III trial
MC4r and ME 