Tag: genetic

MC4r

Rhythm Pharmaceuticals modify design of ongoing MC4r treatment following FDA feedback

First I’ll start with an apology for being MIA; I’ve had the worst spell of migraine attacks. Unfortunately when I have an attack they can last anywhere between a few days to two weeks and I’ve been down for about two weeks. Still not 100% but on the mend. I’ve had a few things I’ve wanted to talk about, but my brain feels like mush … Continue reading Rhythm Pharmaceuticals modify design of ongoing MC4r treatment following FDA feedback

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Weight Loss

Happy New Year: Find what works for you and stick with it

So firstly, apologies for my absence. Just before Christmas I ended up catching COVID, I didn’t really tell anyone about it except the people I had to. I didn’t really want to make a big song and dance about it. Everyone has either had it or will have it at some point. I do have some ongoing issues, which is why I currently sympathise with … Continue reading Happy New Year: Find what works for you and stick with it

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Mental Health

Mental Health: Learning from negative emotions

Every now and then I like to steer away from MC4r and talk about mental health. A persons weight can have a massive impact on their mental health, and it’s reflected in almost everything we see. Recently I found myself in a strange place, and decided to reflect on it. One of the most googled “how to” searches is “how to lose weight” and I’ve … Continue reading Mental Health: Learning from negative emotions

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MC4r

Why finding out if you have a genetic mutation linked to obesity is important

I’ve been a busy little bee, but have come across something fairly interesting. I bring up my childhood frequently — usually in the form of stories and memories that hold significant value to me and my MC4r journey. I bring these up because I think it’s important to understand that a person has demons in their past. Regardless of how small or big they may … Continue reading Why finding out if you have a genetic mutation linked to obesity is important

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Mental Health

Thanks: But you don’t get to have an option about what I eat

The other night I got to thinking and felt like I should do a follow up post to my last regarding the sugar tax levy. Some might read that post and think this girl is on a tangent about something that doesn’t affect me, and has little to do about weight loss. Now, the reason something as minor as taking a full sugar soda option … Continue reading Thanks: But you don’t get to have an option about what I eat

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MC4r

Rhythm Pharmaceuticals announces authorization of IMCIVREE for treatment of obesity in the EU

It’s time for some good news my friends, Rhythm Pharmaceuticals, Inc. who we’ve spoken about a few times have announced that the European Commission has granted marketing authorization to IMCIVREE in the European Union for the treatment of obesity and the control of hunger associated with genetics. Rhythm’s Phase 3 trials confirmed that treatment with IMCIVREE may deliver clinically meaningful impacts on obesity and severe … Continue reading Rhythm Pharmaceuticals announces authorization of IMCIVREE for treatment of obesity in the EU

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Mental Health, Weight Loss

Pupils to be weighed regularly in schools as experts believe lockdown as caused obesity in children

So this is a bit of an impromptu post. When I’m at work I like to spend my lunch hour scanning the news to see what’s going on in the world and I came across this article by The Sun: Primary school pupils ‘to be regularly weighed in class’ over fears Covid pandemic has sparked child obesity crisis — the headline alone was enough to … Continue reading Pupils to be weighed regularly in schools as experts believe lockdown as caused obesity in children

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MC4r

New research suggest many of us could be carrying 17kg of fat due to a disruptive mutation in the MC4r gene

Today we’re going back to basics and talking about the gene that inspired this blog — MC4r. Im always sceptical when I read a headline that says “new research has found…” mostly because in my experience their conclusions are not new, but merely support previous research. So today, when I googled MC4r to see what was going on in the scientific world of weight loss … Continue reading New research suggest many of us could be carrying 17kg of fat due to a disruptive mutation in the MC4r gene

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MC4r

Rhythm Pharmaceuticals’ MC4r agonist drug could be marketed by the end of 2021

Over the last couple of weeks I’ve shared some opinions. You may have agreed with me, you may not but at the end of the day an opinion is just that. An opinion. I don’t pretend to be all knowing. I’m not a scientist, biologist, or nutritionist. I’m just a girl with MC4r deficiency and a weight problem, trying to make sense of everything. In … Continue reading Rhythm Pharmaceuticals’ MC4r agonist drug could be marketed by the end of 2021

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Weight Loss

Your genetics are not your destiny

One of the first things you feel when you’re diagnosed with a genetic mutation that affects your weight, is hopeless. I remember for a brief moment wanting to give up because because I thought — why fight my genetics? I suppose one of the benefits of being diagnosed when I was 18, was that I was already trying to lose weight and had lost weight … Continue reading Your genetics are not your destiny

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MC4r

Researchers have linked 300 mutations to the MC4r gene

After writing last weeks post I asked myself a question, and weirdly it’s a question I’ve never asked myself before. Do we all have a genetic component when it comes to our weight, or just some of us? Well, I couldn’t find the answer — or shall I say, I was unable to find a straight answer. Every study I find only related to participants … Continue reading Researchers have linked 300 mutations to the MC4r gene

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MC4r

Scientists are aware of around 80 different genetic conditions that cause obesity

As stated in an earlier post, I want to talk more about other genetic disorders that are not my own – MC4r deficiency is something I try to educate myself with everyday. A part of me feels like if I can understand what causes my weight problem, I’ll hold less resentment towards it. Scientists are aware of around 80 different genetic conditions that can cause … Continue reading Scientists are aware of around 80 different genetic conditions that cause obesity

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