Scientists link second gene to appetite regulation in MC4r gene

I hope all reading this had a very merry Christmas and are looking forward to the new year! I’ve been out of touch lately and I want to post more frequently in the new year. Hopefully with more positive news such as my last post. Hopefully things continue as they have been and 2023 will shape up to be a good year for those of … Continue reading Scientists link second gene to appetite regulation in MC4r gene

Rhythm Pharmaceuticals has announced the publication of a children’s book “Gabe’s Story”

Last I posted it was with regards to my mental health, while an uphill battle I’m on the mend and seeing better days. I’ve wanted to get back to posting regularly and hope I can put my best foot forward today. I’m going to begin with something that brought a smile to my face when I read it, Rhythm Pharmaceuticals has announced the publication of … Continue reading Rhythm Pharmaceuticals has announced the publication of a children’s book “Gabe’s Story”

Promising new research into MC4r could lead to treatment

So, the other day someone asked me about a drug that has supposedly been submitted to the FDA this year to treat MC4r. Personally I’ve not heard anything about this drug, nor have I been able to find any information about it. However, while trying to find information about it I came across some articles from a couple of months ago, raving about possible new … Continue reading Promising new research into MC4r could lead to treatment

What are MC4r agonists?

As we’ve established on this blog a mutation in the MC4r gene causes early on set obesity. But what is MC4r? Well it’s actually a G-protein-coupled receptor located near the hypothalamus. This receptor has a known ligand which is a small molecule which produces a signal by binding to the site – in this case, the G-protein. It is because of this ligand that scientists … Continue reading What are MC4r agonists?

Four signs and symptoms of MC4r explained without all the science jargon

In my first post I explained MC4r deficiency in a nutshell. However, there is still so much to this gene than just brain chemistry. What I find annoying is that all the scientific research online is just that – scientific research and is so complicated to understand and follow as someone who only has a basic understanding of science. When I was studying journalism at … Continue reading Four signs and symptoms of MC4r explained without all the science jargon